Part II In megaloblastic anaemia EDITORIAL
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چکیده
Bock, 0. A. A., Arapakis, G., Witts, L. J., and Richards, W. C. D. (1963a). The serum pepsinogen level with special reference to the histology of the gastric mucosa. Gut, 4, 106-1 11. Richards, W. C. D., and Witts, L. J. (1963b). The relationship between acid secretion after augmented histamine stimulation and the histology of the gastric mucosa. Ibid., 4, 112-114. Coghill, N. F. (1960). The significance of gastritis. Postgrad. med. J., 36, 733-742. Dacie, J. V. (1956). Practical Haematology, 2nd ed. Churchill, London. Floch, M. H., and Thomassen, R. W. (1963). Gastritis in hookworm disease. Amer. J. dig. Dis., 8, 128-134. Foy, H., and Kondi, A. (1958). Anaemias of the tropics: East Africa. With special reference to proteins and liver damage. Trans. roy. Soc. trop. Med. Hyg., 52, 46-70. ,. (1960). Hookworms in the aetiology of tropical iron deficiency anaemia. Ibid., 54,419-433. Jacobs, A. (1963). Epithelial changes in anaemic East Africans. Brit. med. J., 1, 1711-1712. Kay, A. W. (1953). Effect of large doses of histamine on gastric secretion of HCI: an augmented histamine test. Ibid., 2, 77-80. Ramsay, W. N. M. (1957). The determination of iron in blood plasma or serum. Clin. Chim. Acta, 2, 214-220. Whitby L. E. H., and Britton, C. J. C. (1957). Disorders of the Blood, 8th ed. Churchill, London. Witts, L. J., (1956). Anaemia and the alimentary tract. The relationship between changes in the alimentary tract and deficiencies of iron, folic acid and vitamin B1,. Publ. roy. Coil. Phycns Edinb., 7, 3. Wood, I. J., Doig, R. K., Motteram, R., and Hughes, A. (1949). Gastric biopsy. Report on 55 biopsies using a new flexible gastric biopsy tube. Lancet, 1, 18-21.
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Enzymatic release of folate activity from the red cells in megaloblastic anaemia of pregnancy.
The content of folate activity precursors in washed red cells and the enzymatic plasma factor activity, necessary for the release of folate from the precursors, were studied in normal subjects and in patients with megaloblastic anaemia of pregnancy. Subjects with megaloblastic anaemia of pregnancy had a significantly reduced folate activity precursor content, and 14 subjects (58%) had significa...
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It has been shown that the incidence of megaloblastic anaemia in a group of 463 randomly selected pregnant women receiving iron was 12 times as high as in a control group of 235 pregnant women receiving iron and folic acid. The incidence of all types of anaemia in the women receiving iron alone was more than three times the incidence in those having iron and folic acid. Some women who were not ...
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Direct destruction and ineffective erythropoesis does not adequately explain the cause of anaemia in malaria. It is possible that there are more other mechanisms involved besides the causes described till date in malarial anaemia. The effect of NO on erythropoesis and a major haematological abnormality (microcytic/normocytic/megaloblastic picture) can significantly be observed on repeated expos...
متن کاملAn account of 335 cases of megaloblastic anaemia of pregnancy and the puerperium.
The incidence of megaloblastic anaemia in pregnancy and the puerperium in north Staffordshire has steadily declined as a result of prophylaxis with folic acid. In the presence of advanced folic acid deficiency and with a florid megaloblastic marrow, the anaemia is usually severe, but in many patients the disease is relatively mild and the degree of anaemia is determined more by blood loss or as...
متن کاملMegaloblastic Anaemia in Premature Infants.
The common anaemia in premature infants is iron deficiency anaemia, but megaloblastic anaemia can also occur and here we report three such cases. Our interest in megaloblastic anaemia was stimulated by a recent case in which megaloblastic anaemia developed when a low phenylalanine diet was being given for treatment of phenylketonuria (Royston and Parry, 1962). In the discussion of this paper Ro...
متن کاملRare case with megaloblastic anaemia.
A nine years old boy presented with history of pallor and anaemia since early infancy along with neural hearing loss responding to empirical multivitamin and folic acid therapy started on basis of blood complete picture showing anaemia and megaloblastic anaemia. On investigation he was diagnosed with Thiamine Responsive Megaloblastic Anaemia, a very rare condition in our settings.
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